Gtpbp10 | GTP-binding protein 10 (putative)

GeneMGI:2385599Synonyms: 4930545J22Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased grip strength	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Late adult	3.95x10^-5
abnormal vibrissa morphology	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Late adult	8.3x10^-7
increased heart rate	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Late adult	6.62x10^-5
increased hemoglobin content	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Early adult	8.38x10^-6
increased circulating creatinine level	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Late adult	1.25x10^-5
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Early adult	2.03x10^-7
abnormal lens morphology	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Late adult	4.12x10^-8
abnormal cornea morphology	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Late adult	2.77x10^-5
increased bone mineral content	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Late adult	6.44x10^-5
decreased mean corpuscular volume	1 supporting dataset	Gtpbp10^{tm1b(KOMP)Mbp}	homozygote	Early adult	4.17x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gtpbp10.

Associated images

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Histopathology

There is no histopathology data found for Gtpbp10.

IMPC related publications

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External links

No external links available for Gtpbp10.

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*Gtpbp10^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gtpbp10^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gtpbp10^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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