Fras1 | Fraser extracellular matrix complex subunit 1

GeneMGI:2385368Synonyms: E130113P14Rik, bl

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Respiratory system Hematopoietic system Behavior/neurological Skeleton Mortality/aging

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal spleen morphology2 supporting datasetsFras1em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal vertebrae morphology1 supporting datasetFras1em1(IMPC)CcpczheterozygoteEarly adult3.78x10-6 
increased airway resistance1 supporting datasetFras1em1(IMPC)CcpczheterozygoteEarly adult1.72x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetFras1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased lung tissue damping1 supporting datasetFras1em1(IMPC)CcpczheterozygoteEarly adult6.93x10-5 
increased freezing behavior1 supporting datasetFras1em1(IMPC)CcpczheterozygoteEarly adult6.76x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fras1em1(IMPC)CcpczExon Deletionmouse

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