Acsm2 | acyl-CoA synthetase medium-chain family member 2

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

abnormal coat appearance1 supporting datasetAcsm2tm1.1(KOMP)VlcghomozygoteEarly adult2.06x10-10 
decreased circulating glucose level1 supporting datasetAcsm2tm1.1(KOMP)VlcghomozygoteEarly adult6.46x10-5 
decreased circulating chloride level1 supporting datasetAcsm2tm1.1(KOMP)VlcghomozygoteEarly adult2.67x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Acsm2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Acsm2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Acsm2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Acsm2tm3a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Acsm2tm3e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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