Tcaf2 | TRPM8 channel-associated factor 2

GeneMGI:2385258Synonyms: Fam115c

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Muscle Vision/eye Hematopoietic system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged thymus1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal skeletal muscle morphology1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased erythrocyte cell number1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adult8.45x10-6 
abnormal eye morphology1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetTcaf2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tcaf2em1(IMPC)CcpczExon Deletionmouse
Tcaf2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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