Gys2 | glycogen synthase 2

GeneMGI:2385254Synonyms: glycogen synthase, liver, LGS

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Adipose tissue Growth/size/body region Skeleton

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating chloride level	1 supporting dataset	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.35x10^-6
increased circulating sodium level	1 supporting dataset	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.2x10^-11
increased bone mineral density	1 supporting dataset	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.67x10^-5
increased lean body mass	2 supporting datasets	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.27x10^-5
increased circulating total protein level	2 supporting datasets	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.72x10^-6
decreased circulating glucose level	3 supporting datasets	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.55x10^-26
abnormal vibrissa morphology	1 supporting dataset	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.19x10^-5
decreased circulating glycerol level	1 supporting dataset	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.36x10^-6
increased circulating calcium level	2 supporting datasets	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.07x10^-6
decreased body weight	1 supporting dataset	Gys2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.16x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gys2.

Associated images

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Histopathology

There is no histopathology data found for Gys2.

IMPC related publications

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External links

No external links available for Gys2.

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*Gys2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

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