Hdac11 | histone deacetylase 11

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating alanine transaminase level1 supporting datasetHdac11em1(IMPC)KmpchomozygoteEarly adult4.34x10-12 
increased body length1 supporting datasetHdac11em1(IMPC)KmpchomozygoteEarly adult3.51x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hdac11em1(IMPC)KmpcDeletionmouse
Hdac11tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Hdac11tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Hdac11tm39814(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Hdac11tm39814(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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