Ahcyl1 | S-adenosylhomocysteine hydrolase-like 1

GeneMGI:2385184Synonyms: IRBIT, Ahcy-rs3, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean platelet volume	1 supporting dataset	Ahcyl1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.57x10^-5
abnormal cornea morphology	1 supporting dataset	Ahcyl1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.41x10^-5
abnormal retina morphology	1 supporting dataset	Ahcyl1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.58x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Ahcyl1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.13x10^-7
increased bone mineral content	1 supporting dataset	Ahcyl1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.54x10^-6
increased circulating thyroxine level	1 supporting dataset	Ahcyl1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.95x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ahcyl1.

Associated images

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Histopathology

There is no histopathology data found for Ahcyl1.

IMPC related publications

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External links

No external links available for Ahcyl1.

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*Ahcyl1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ahcyl1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

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