Msto1 | misato 1, mitochondrial distribution and morphology regulator

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Mortality/aging Renal/urinary system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Msto1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Msto1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Msto1^em1(IMPC)Tcp	heterozygote	Early adult	2.11x10^-7
increased circulating triglyceride level	1 supporting dataset	Msto1^em1(IMPC)Tcp	heterozygote	Early adult	1.96x10^-5
enlarged lymph nodes	1 supporting dataset	Msto1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Msto1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Msto1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Msto1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Msto1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Msto1.

IMPC related publications

Loading...

External links

No external links available for Msto1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Msto1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Msto1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Msto1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

My Genes