Ncoa5 | nuclear receptor coactivator 5

GeneMGI:2385165

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Ncoa5^{tm1.1(KOMP)Mbp}	homozygote	E12.5	N/A ^*
increased heart weight	2 supporting datasets	Ncoa5^{tm1.1(KOMP)Mbp}	heterozygote	Early adult	2.21x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Ncoa5^{tm1.1(KOMP)Mbp}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Ncoa5^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
increased eosinophil cell number	1 supporting dataset	Ncoa5^{tm1.1(KOMP)Mbp}	heterozygote	Early adult	6.46x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ncoa5.

Associated images

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Histopathology

There is no histopathology data found for Ncoa5.

IMPC related publications

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External links

No external links available for Ncoa5.

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*Ncoa5^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Ncoa5^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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