Btbd3 | BTB domain containing 3

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton

16 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
35Embryo tissues

Phenotypes

abnormal vertebral arch morphology2 supporting datasetsBtbd3tm1b(EUCOMM)HmguhomozygoteEarly adult1.51x10-5 
enlarged thyroid gland2 supporting datasetsBtbd3tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased body weight1 supporting datasetBtbd3tm1b(EUCOMM)HmguhomozygoteEarly adult1.67x10-5 
increased CD8-positive, CD25-positive alpha-beta T cell number1 supporting datasetBtbd3tm1b(EUCOMM)HmguhomozygoteEarly adult6.68x10-6 
abnormal vertebrae morphology1 supporting datasetBtbd3tm1b(EUCOMM)HmguhomozygoteEarly adult2.11x10-5 
abnormal thyroid gland morphology2 supporting datasetsBtbd3tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Btbd3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Btbd3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Btbd3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Btbd3tm1c(EUCOMM)HmguWild type floxed exon (post-Flp)mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter