Cdca7l | cell division cycle associated 7 like

GeneMGI:2384982Synonyms: JPO2

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Growth/size/body region Hematopoietic system Renal/urinary system

14 No significant impact

4 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adultN/A * 
increased circulating cholesterol level1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adult5.87x10-7 
abnormal lymph node morphology1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adultN/A * 
small kidney1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adultN/A * 
enlarged spleen1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adultN/A * 
enlarged lymph nodes1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal spleen morphology1 supporting datasetCdca7lem1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdca7lem1(IMPC)MbpIntra-exon deletionmouse
Cdca7ltm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cdca7ltm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Cdca7ltm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cdca7ltm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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