Rxylt1 | ribitol xylosyltransferase 1

GeneMGI:2384919Synonyms: 6330415D21Rik, Tmem5

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Pigmentation Integument Vision/eye Behavior/neurological Cardiovascular system Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength2 supporting datasetsRxylt1em1(IMPC)JheterozygoteEarly adult2.26x10-5 
impaired righting response1 supporting datasetRxylt1em1(IMPC)JheterozygoteLate adult3.16x10-6 
abnormal coat/hair pigmentation1 supporting datasetRxylt1em1(IMPC)JheterozygoteLate adult8.88x10-7 
limb grasping1 supporting datasetRxylt1em1(IMPC)JheterozygoteLate adult1.72x10-6 
abnormal retina blood vessel morphology1 supporting datasetRxylt1em1(IMPC)JheterozygoteEarly adult7.21x10-5 
hyperactivity2 supporting datasetsRxylt1em1(IMPC)JheterozygoteEarly adult6.96x10-6 
abnormal coat/ hair morphology1 supporting datasetRxylt1em1(IMPC)JheterozygoteLate adult1.86x10-5 
preweaning lethality, complete penetrance1 supporting datasetRxylt1em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rxylt1em1(IMPC)JExon Deletionmouse
Rxylt1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rxylt1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Rxylt1tm45895(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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