Appl2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

GeneMGI:2384914Synonyms: Dip3b

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

18 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes



increased circulating LDL cholesterol level	1 supporting dataset		Appl2^{tm1a(KOMP)Wtsi}	homozygote	Early adult		1.36x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Appl2.

Associated images

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Histopathology

There is no histopathology data found for Appl2.

IMPC related publications

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External links

No external links available for Appl2.

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*Appl2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Appl2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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