Hkdc1 | hexokinase domain containing 1

GeneMGI:2384910

Physiological systems

14 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Skeleton

11 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral density	1 supporting dataset	Hkdc1^em1(IMPC)Bay	homozygote	Early adult	1.98x10^-5
increased total body fat amount	2 supporting datasets	Hkdc1^em1(IMPC)Bay	homozygote	Early adult	1.85x10^-7
decreased bone mineral content	1 supporting dataset	Hkdc1^em1(IMPC)Bay	homozygote	Early adult	3.34x10^-5
decreased lean body mass	2 supporting datasets	Hkdc1^em1(IMPC)Bay	homozygote	Early adult	4.96x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hkdc1.

Associated images

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Histopathology

There is no histopathology data found for Hkdc1.

IMPC related publications

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External links

No external links available for Hkdc1.

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*Hkdc1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Hkdc1^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Hkdc1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Hkdc1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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