Micu1 | mitochondrial calcium uptake 1

GeneMGI:2384909Synonyms: Cbara1, C730016L05Rik

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Mortality/aging Craniofacial

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal gait	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	7.75x10^-5
abnormal tail length	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	5.32x10^-6
long tibia	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	4.92x10^-9
abnormal snout morphology	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	4.9x10^-5
abnormal locomotor behavior	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	3.95x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	N/A ^*
increased total body fat amount	2 supporting datasets	Micu1^tm1bNarl	heterozygote	Early adult	1.2x10^-9
decreased mean platelet volume	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	4.16x10^-6
decreased monocyte cell number	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	8.85x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	4.03x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Micu1.

Associated images

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Histopathology

There is no histopathology data found for Micu1.

IMPC related publications

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External links

No external links available for Micu1.

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*Micu1^{tm197763(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Micu1^tm1aNarl*	KO first allele (reporter-tagged insertion with conditional potential)	‌	ES Cell mouse
*Micu1^tm1bNarl*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Micu1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Micu1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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