Micu1 | mitochondrial calcium uptake 1

GeneMGI:2384909Synonyms: Cbara1, C730016L05Rik

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Mortality/aging Craniofacial

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal gait	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	7.75x10^-5
abnormal tail length	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	5.32x10^-6
long tibia	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	4.92x10^-9
abnormal snout morphology	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	4.9x10^-5
abnormal locomotor behavior	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	3.95x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Micu1^tm1bNarl	homozygote	Early adult	N/A ^*
increased total body fat amount	2 supporting datasets	Micu1^tm1bNarl	heterozygote	Early adult	1.2x10^-9
decreased mean platelet volume	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	4.16x10^-6
decreased monocyte cell number	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	8.85x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Micu1^tm1bNarl	heterozygote	Early adult	4.03x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Micu1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Micu1.

IMPC related publications

Loading...

External links

No external links available for Micu1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Micu1^{tm197763(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Micu1^tm1aNarl*	KO first allele (reporter-tagged insertion with conditional potential)	‌	es cell mouse
*Micu1^tm1bNarl*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Micu1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Micu1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes