Ginm1 | glycoprotein integral membrane 1

GeneMGI:2384905Synonyms: BC013529

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Vision/eye Mortality/aging

15 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
0Embryo tissues

Phenotypes

abnormal optic disk morphology1 supporting datasetGinm1tm1b(EUCOMM)WtsihomozygoteEarly adult3.52x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetGinm1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal retina inner nuclear layer morphology2 supporting datasetsGinm1tm1b(EUCOMM)WtsihomozygoteEarly adult4.7x10-6 
decreased total retina thickness2 supporting datasetsGinm1tm1b(EUCOMM)WtsihomozygoteEarly adult1.08x10-11 
abnormal retina outer nuclear layer morphology2 supporting datasetsGinm1tm1b(EUCOMM)WtsihomozygoteEarly adult1.99x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ginm1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ginm1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ginm1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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