Antkmt | adenine nucleotide translocase lysine methyltransferase

GeneMGI:2384888Synonyms: Fam173a

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Behavior/neurological

18 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

hyperactivity5 supporting datasetsAntkmttm1.1(KOMP)VlcghomozygoteEarly adult5.53x10-10 
decreased thigmotaxis2 supporting datasetsAntkmttm1.1(KOMP)VlcghomozygoteEarly adult6.27x10-5 
abnormal uterus morphology1 supporting datasetAntkmttm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetAntkmttm1.1(KOMP)VlcghomozygoteEarly adult1.24x10-29 
increased circulating aspartate transaminase level1 supporting datasetAntkmttm1.1(KOMP)VlcghomozygoteEarly adult3.89x10-13 
abnormal behavior1 supporting datasetAntkmttm1.1(KOMP)VlcghomozygoteEarly adult6.29x10-5 
hydrometra1 supporting datasetAntkmttm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Antkmttm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Antkmttm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Antkmttm214610(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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