Chtf18 | CTF18, chromosome transmission fidelity factor 18
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging Cardiovascular system
13 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
46Embryo tissues
| increased circulating chloride level | 1 supporting dataset | Chtf18tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.9x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Chtf18tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| increased heart weight | 1 supporting dataset | Chtf18tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.26x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Chtf18tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| hyperactivity | 2 supporting datasets | Chtf18tm1b(KOMP)Wtsi | heterozygote | Early adult | 5.76x10-9 | ||
| increased circulating bilirubin level | 1 supporting dataset | Chtf18tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.81x10-5 |
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External links
No external links available for Chtf18.
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| Chtf18tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Chtf18tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Chtf18tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Chtf18tm95093(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |