Slc44a3 | solute carrier family 44, member 3

GeneMGI:2384860

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal lens morphology	2 supporting datasets	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.42x10^-6
persistence of hyaloid vascular system	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.79x10^-6
abnormal retina morphology	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.45x10^-8
abnormal retina blood vessel morphology	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.69x10^-6
decreased exploration in new environment	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.27x10^-14
abnormal retina vasculature morphology	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.82x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.01x10^-6
abnormal vitreous body morphology	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.1x10^-6
cataract	1 supporting dataset	Slc44a3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.6x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc44a3.

Associated images

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Histopathology

There is no histopathology data found for Slc44a3.

IMPC related publications

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External links

No external links available for Slc44a3.

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*Slc44a3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Slc44a3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc44a3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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