Ap1ar | adaptor-related protein complex 1 associated regulatory protein
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Integument Growth/size/body region Vision/eye Skeleton Cardiovascular system
13 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| decreased total retina thickness | 2 supporting datasets | Ap1artm2b(EUCOMM)Hmgu | homozygote | Early adult | 3x10-10 | ||
| increased bone mineral content | 1 supporting dataset | Ap1artm2b(EUCOMM)Hmgu | homozygote | Early adult | 2.48x10-5 | ||
| increased lean body mass | 2 supporting datasets | Ap1artm2b(EUCOMM)Hmgu | homozygote | Early adult | 2.34x10-7 | ||
| abnormal retina inner nuclear layer morphology | 1 supporting dataset | Ap1artm2b(EUCOMM)Hmgu | homozygote | Early adult | 3.69x10-5 | ||
| increased heart weight | 1 supporting dataset | Ap1artm2b(EUCOMM)Hmgu | homozygote | Early adult | 1.11x10-8 | ||
| abnormal coat appearance | 2 supporting datasets | Ap1artm2b(EUCOMM)Hmgu | homozygote | Early adult | 6.8x10-13 |
| | | | | | | | | | |
External links
No external links available for Ap1ar.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ap1artm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Ap1artm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |
| Ap1artm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Ap1artm2b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |