Lpcat1 | lysophosphatidylcholine acyltransferase 1

GeneMGI:2384812Synonyms: Aytl2, rd11, +2 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Cardiovascular system

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Lpcat1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.15x10^-16
mydriasis	1 supporting dataset	Lpcat1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.97x10^-16
abnormal retina vasculature morphology	1 supporting dataset	Lpcat1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.82x10^-8
hyperactivity	1 supporting dataset	Lpcat1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.58x10^-5
impaired pupillary reflex	1 supporting dataset	Lpcat1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.64x10^-15

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lpcat1.

Associated images

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Histopathology

There is no histopathology data found for Lpcat1.

IMPC related publications

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External links

No external links available for Lpcat1.

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*Lpcat1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Lpcat1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Lpcat1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Lpcat1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Lpcat1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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