Pycr1 | pyrroline-5-carboxylate reductase 1

GeneMGI:2384795

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

5Associated diseases

Expression examined in:48Adult tissues

47Embryo tissues

Phenotypes



decreased circulating free fatty acids level	1 supporting dataset		Pycr1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult		6.13x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pycr1.

Associated images

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Histopathology

There is no histopathology data found for Pycr1.

IMPC related publications

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External links

No external links available for Pycr1.

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*Pycr1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Pycr1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Pycr1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Pycr1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pycr1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pycr1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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