Akr1d1 | aldo-keto reductase family 1, member D1

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

hyperactivity3 supporting datasetsAkr1d1tm1.1(KOMP)VlcghomozygoteEarly adult5.54x10-7 
persistence of hyaloid vascular system1 supporting datasetAkr1d1tm1.1(KOMP)VlcghomozygoteEarly adult4.97x10-5 
increased grip strength1 supporting datasetAkr1d1tm1.1(KOMP)VlcghomozygoteEarly adult1.84x10-6 
decreased fasting circulating glucose level1 supporting datasetAkr1d1tm1.1(KOMP)VlcghomozygoteEarly adult6.1x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Akr1d1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Akr1d1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Akr1d1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Akr1d1tm3a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Akr1d1tm3e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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