Ndrg4 | N-myc downstream regulated gene 4
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Muscle Behavior/neurological Cardiovascular system
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| hyperactivity | 8 supporting datasets | Ndrg4tm1b(KOMP)Wtsi | homozygote | Early adult | 1.2x10-18 | ||
| decreased cardiac muscle contractility | 1 supporting dataset | Ndrg4tm1b(KOMP)Wtsi | homozygote | Early adult | 4.36x10-5 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Ndrg4tm1b(KOMP)Wtsi | homozygote | Early adult | 6.87x10-8 | ||
| limb grasping | 1 supporting dataset | Ndrg4tm1b(KOMP)Wtsi | homozygote | Early adult | 9.41x10-7 | ||
| increased circulating creatinine level | 1 supporting dataset | Ndrg4tm1b(KOMP)Wtsi | homozygote | Early adult | 1.53x10-6 | ||
| abnormal gait | 1 supporting dataset | Ndrg4tm1b(KOMP)Wtsi | homozygote | Early adult | 6.29x10-10 |
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External links
No external links available for Ndrg4.
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| Ndrg4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ndrg4tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ndrg4tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |