Zfp280d | zinc finger protein 280D

GeneMGI:2384583Synonyms: Suhw4

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Muscle Nervous system Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased startle reflex	1 supporting dataset	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	1.08x10^-16
decreased locomotor activity	2 supporting datasets	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	3.31x10^-5
dilated heart left ventricle	2 supporting datasets	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	5.54x10^-24
decreased prepulse inhibition	4 supporting datasets	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	1.02x10^-9
prolonged QRS complex duration	1 supporting dataset	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	1.66x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	3.7x10^-5
decreased cardiac muscle contractility	2 supporting datasets	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	4.28x10^-34
increased circulating aspartate transaminase level	1 supporting dataset	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	7.26x10^-6
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	3.14x10^-5
abnormal startle reflex	1 supporting dataset	Zfp280d^{em1(IMPC)Hmgu}	homozygote	Early adult	8.06x10^-14

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zfp280d.

Associated images

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Histopathology

There is no histopathology data found for Zfp280d.

IMPC related publications

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External links

No external links available for Zfp280d.

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*Zfp280d^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Zfp280d^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zfp280d^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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