Il27 | interleukin 27

GeneMGI:2384409Synonyms: IL-27p28, Il30, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased CD4-positive, alpha-beta memory T cell number	1 supporting dataset	Il27^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number	1 supporting dataset	Il27^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Il27.

Associated images

Loading...

Histopathology

There is no histopathology data found for Il27.

IMPC related publications

Loading...

External links

No external links available for Il27.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Il27^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Il27^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Il27^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes