Usp11 | ubiquitin specific peptidase 11

GeneMGI:2384312Synonyms: 6230415D12Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating HDL cholesterol level1 supporting datasetUsp11tm1(KOMP)WtsihemizygoteEarly adult3.26x10-6 
increased circulating LDL cholesterol level1 supporting datasetUsp11tm1(KOMP)WtsihemizygoteEarly adult1.11x10-6 
increased mean corpuscular hemoglobin1 supporting datasetUsp11tm1(KOMP)WtsihomozygoteEarly adult5.66x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Usp11em1(IMPC)MarcDeletionmouse
Usp11tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
mouse

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