Sbno1 | strawberry notch 1

GeneMGI:2384298Synonyms: 9330180L10Rik, sno

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Immune system Integument Hematopoietic system Mortality/aging

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
abnormal coat appearance	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.3x10^-6
increased circulating fructosamine level	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.25x10^-5
increased leukocyte cell number	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.72x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.7x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Sbno1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.59x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sbno1.

Associated images

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Histopathology

There is no histopathology data found for Sbno1.

IMPC related publications

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External links

No external links available for Sbno1.

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*Sbno1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Sbno1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Sbno1^{tm300560(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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