Cd276 | CD276 antigen

GeneMGI:2183926Synonyms: B7RP-2, B7-H3, +2 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity1 supporting datasetCd276tm2b(EUCOMM)HmguhomozygoteEarly adult5.69x10-5 
increased circulating total protein level1 supporting datasetCd276tm2b(EUCOMM)HmguhomozygoteEarly adult8.83x10-5 
decreased mean corpuscular volume1 supporting datasetCd276tm2b(EUCOMM)HmguhomozygoteEarly adult4.43x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cd276tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Cd276tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cd276tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cd276tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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