Psat1 | phosphoserine aminotransferase 1

GeneMGI:2183441Synonyms: EPIP, D8Ertd814e, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased blood urea nitrogen level1 supporting datasetPsat1tm1a(KOMP)WtsiheterozygoteEarly adult6.32x10-5 
preweaning lethality, complete penetrance1 supporting datasetPsat1tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal tail movements1 supporting datasetPsat1tm1a(KOMP)WtsiheterozygoteEarly adult7.74x10-6 
decreased circulating aspartate transaminase level1 supporting datasetPsat1tm1a(KOMP)WtsiheterozygoteEarly adult5.3x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Psat1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Psat1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Psat1tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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