Nrbp1 | nuclear receptor binding protein 1

GeneMGI:2183436Synonyms: Nrbp, B230344L17Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased grip strength	2 supporting datasets	Nrbp1^{tm3b(EUCOMM)Wtsi}	heterozygote	Early adult	1.04x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Nrbp1^{tm3b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased CD8-positive, alpha-beta T cell number	1 supporting dataset	Nrbp1^{tm3b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
decreased CD4-positive, alpha-beta T cell number	1 supporting dataset	Nrbp1^{tm3b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nrbp1.

Associated images

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Histopathology

There is no histopathology data found for Nrbp1.

IMPC related publications

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External links

No external links available for Nrbp1.

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*Nrbp1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Nrbp1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nrbp1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nrbp1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nrbp1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nrbp1^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Nrbp1^{tm3b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nrbp1^{tm3e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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