Nadk | NAD kinase

GeneMGI:2183149Synonyms: 4432404C02Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Skeleton Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsNadkem2(IMPC)BayhomozygoteEarly adultN/A * 
increased bone mineral content1 supporting datasetNadkem2(IMPC)BayheterozygoteEarly adult2.74x10-5 
embryonic lethality prior to organogenesis1 supporting datasetNadkem2(IMPC)BayhomozygoteE9.5N/A * 
increased lean body mass1 supporting datasetNadkem2(IMPC)BayheterozygoteEarly adult9.37x10-6 
decreased total body fat amount1 supporting datasetNadkem2(IMPC)BayheterozygoteEarly adult2.06x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nadkem1(IMPC)Baymouse
Nadkem2(IMPC)BayExon Deletionmouse
Nadktm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nadktm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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