Adgrf5 | adhesion G protein-coupled receptor F5

GeneMGI:2182928Synonyms: 8430401C09Rik, Gpr116

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.46x10^-19
decreased monocyte cell number	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.52x10^-5
decreased mean corpuscular volume	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.3x10^-8
decreased leukocyte cell number	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.91x10^-7
decreased lymphocyte cell number	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.24x10^-5
decreased hematocrit	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.04x10^-5
decreased hemoglobin content	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.1x10^-15
impaired glucose tolerance	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.93x10^-6
decreased circulating cholesterol level	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.69x10^-5
increased red blood cell distribution width	1 supporting dataset	Adgrf5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.31x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adgrf5.

Associated images

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Histopathology

There is no histopathology data found for Adgrf5.

IMPC related publications

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External links

No external links available for Adgrf5.

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*Adgrf5^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Adgrf5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Adgrf5^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Adgrf5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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