Serpina3i | serine (or cysteine) peptidase inhibitor, clade A, member 3I

GeneMGI:2182841Synonyms: alpha-1 antiproteinase, Gm6930, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Hearing/vestibular/ear Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased exploration in new environment1 supporting datasetSerpina3iem1(IMPC)JhomozygoteEarly adult7.71x10-5 
hyperactivity2 supporting datasetsSerpina3iem1(IMPC)JhomozygoteEarly adult1.09x10-5 
increased grip strength2 supporting datasetsSerpina3iem1(IMPC)JhomozygoteEarly adult1.31x10-7 
decreased leukocyte cell number1 supporting datasetSerpina3iem1(IMPC)JhomozygoteEarly adult1.09x10-5 
increased vertical activity1 supporting datasetSerpina3iem1(IMPC)JhomozygoteEarly adult3.64x10-5 
abnormal auditory brainstem response1 supporting datasetSerpina3iem1(IMPC)JhomozygoteEarly adult5.68x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Serpina3iem1(IMPC)JExon Deletionmouse

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