Carf | calcium response factor

GeneMGI:2182269Synonyms: Als2cr8

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Cardiovascular system

15 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

prolonged ST segment1 supporting datasetCarftm1.1(KOMP)VlcghomozygoteEarly adult9.85x10-7 
increased circulating sodium level1 supporting datasetCarftm1.1(KOMP)VlcghomozygoteEarly adult1.56x10-5 
increased circulating chloride level1 supporting datasetCarftm1.1(KOMP)VlcghomozygoteEarly adult8.31x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Carftm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Carftm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Carftm41567(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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