Hook2 | hook microtubule tethering protein 2

GeneMGI:2181664Synonyms: A630054I03Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Vision/eye Hematopoietic system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small seminal vesicle	1 supporting dataset	Hook2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Hook2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Hook2^em1(IMPC)Tcp	homozygote	Early adult	4.87x10^-5
increased red blood cell distribution width	1 supporting dataset	Hook2^em1(IMPC)Tcp	homozygote	Early adult	1.19x10^-5
abnormal skin morphology	1 supporting dataset	Hook2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Hook2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hook2.

Associated images

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Histopathology

There is no histopathology data found for Hook2.

IMPC related publications

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External links

No external links available for Hook2.

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*Hook2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Hook2^{tm1a(NCOM)Mfgc}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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