Dennd2d | DENN domain containing 2D

GeneMGI:2181193Synonyms: 2010308M01Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Nervous system Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Dennd2d^{tm2b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	1 supporting dataset	Dennd2d^{tm2b(KOMP)Mbp}	homozygote	Early adult	6.39x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dennd2d.

Associated images

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Histopathology

There is no histopathology data found for Dennd2d.

IMPC related publications

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External links

No external links available for Dennd2d.

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*Dennd2d^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dennd2d^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Dennd2d^{tm2a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dennd2d^{tm2b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dennd2d^{tm41823(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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