Atp13a1 | ATPase type 13A1

GeneMGI:2180801Synonyms: Atp13a, Cgi152, +1 more

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Embryo Growth/size/body region Nervous system Vision/eye Mortality/aging Craniofacial

12 No significant impact

4 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal head shape1 supporting datasetAtp13a1em1(IMPC)TcphomozygoteE15.5N/A * 
anophthalmia1 supporting datasetAtp13a1em1(IMPC)TcphomozygoteE15.5N/A * 
edema1 supporting datasetAtp13a1em1(IMPC)TcphomozygoteE15.5N/A * 
abnormal embryo size1 supporting datasetAtp13a1em1(IMPC)TcphomozygoteE15.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsAtp13a1em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetAtp13a1em1(IMPC)TcphomozygoteE9.5N/A * 
anophthalmia1 supporting datasetAtp13a1em1(IMPC)TcpheterozygoteE15.5N/A * 
abnormal head size1 supporting datasetAtp13a1em1(IMPC)TcpheterozygoteE15.5N/A * 
abnormal craniofacial morphology1 supporting datasetAtp13a1em1(IMPC)TcphomozygoteE15.5N/A * 
exencephaly1 supporting datasetAtp13a1em1(IMPC)TcphomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atp13a1em1(IMPC)TcpExon Deletionmouse
Atp13a1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Atp13a1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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