Mtmr4 | myotubularin related protein 4

GeneMGI:2180699Synonyms: ZFYVE11, ESTM44, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Mortality/aging Renal/urinary system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Mtmr4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal urination	1 supporting dataset	Mtmr4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.76x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mtmr4.

Associated images

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Histopathology

There is no histopathology data found for Mtmr4.

IMPC related publications

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External links

No external links available for Mtmr4.

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*Mtmr4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Mtmr4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mtmr4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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