Mtmr4 | myotubularin related protein 4

GeneMGI:2180699Synonyms: ZFYVE11, ESTM44, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Mortality/aging Renal/urinary system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetMtmr4tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal urination1 supporting datasetMtmr4tm1a(EUCOMM)WtsiheterozygoteEarly adult1.76x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mtmr4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Mtmr4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Mtmr4tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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