Atpaf2 | ATP synthase mitochondrial F1 complex assembly factor 2

GeneMGI:2180561Synonyms: ATP12, ATP12p

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Behavior/neurological Skeleton Craniofacial Mortality/aging

16 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetAtpaf2tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal vertebrae morphology1 supporting datasetAtpaf2tm1a(KOMP)WtsiheterozygoteEarly adult6.12x10-5 
abnormal maxilla morphology1 supporting datasetAtpaf2tm1a(KOMP)WtsiheterozygoteEarly adult1.47x10-5 
decreased locomotor activity1 supporting datasetAtpaf2tm1a(KOMP)WtsiheterozygoteEarly adult8.52x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atpaf2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Atpaf2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Atpaf2tm300104(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Atpaf2tm37876(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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