Casc3 | exon junction complex subunit
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Embryo Growth/size/body region Mortality/aging
17 No significant impact
2 Not tested
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
| abnormal epididymis morphology | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| enlarged epididymis | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| decreased blood urea nitrogen level | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.15x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Casc3tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Casc3tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
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External links
No external links available for Casc3.
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