Mycbp2 | MYC binding protein 2, E3 ubiquitin protein ligase
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Cardiovascular system Mortality/aging
17 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal placenta morphology | 1 supporting dataset | Mycbp2em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Mycbp2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged heart | 1 supporting dataset | Mycbp2em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Mycbp2em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal placenta vasculature | 1 supporting dataset | Mycbp2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| anophthalmia | 1 supporting dataset | Mycbp2em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Mycbp2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Mycbp2em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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External links
No external links available for Mycbp2.
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| Mycbp2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Mycbp2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Mycbp2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Mycbp2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |