Cacna1i | calcium channel, voltage-dependent, alpha 1I subunit
GeneMGI:2178051
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system
13 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| increased circulating chloride level | 1 supporting dataset | Cacna1itm1b(KOMP)Wtsi | homozygote | Early adult | 2.06x10-6 | ||
| abnormal pancreas morphology | 1 supporting dataset | Cacna1itm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| small liver | 1 supporting dataset | Cacna1itm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Cacna1itm1b(KOMP)Wtsi | homozygote | Early adult | 8.85x10-5 | ||
| increased heart weight | 1 supporting dataset | Cacna1itm1b(KOMP)Wtsi | homozygote | Early adult | 2.19x10-5 | ||
| small heart | 1 supporting dataset | Cacna1itm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Cacna1itm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Cacna1i.
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| Cacna1itm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Cacna1itm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Cacna1itm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |