Acot3 | acyl-CoA thioesterase 3

GeneMGI:2159619Synonyms: Pte2a, PTE-Ia

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Behavior/neurological Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased exploration in new environment	1 supporting dataset	Acot3^em1(IMPC)Mbp	homozygote	Early adult	2.06x10^-8
abnormal eye morphology	1 supporting dataset	Acot3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Acot3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased freezing behavior	1 supporting dataset	Acot3^em1(IMPC)Mbp	homozygote	Early adult	9.34x10^-6
abnormal kidney morphology	1 supporting dataset	Acot3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
microphthalmia	1 supporting dataset	Acot3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Acot3.

Associated images

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Histopathology

There is no histopathology data found for Acot3.

IMPC related publications

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External links

No external links available for Acot3.

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*Acot3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Acot3^{tm45747(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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