Arr3 | arrestin 3, retinal

GeneMGI:2159617Synonyms: arrestin 4, X-arrestin, +5 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

impaired pupillary reflex1 supporting datasetArr3em1(IMPC)JhemizygoteEarly adult2.93x10-7 
decreased circulating triglyceride level1 supporting datasetArr3em1(IMPC)JhomozygoteEarly adult3.99x10-7 
increased circulating alkaline phosphatase level1 supporting datasetArr3em1(IMPC)JhomozygoteEarly adult2.19x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arr3em1(IMPC)JExon Deletionmouse
Arr3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Arr3tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Arr3tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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