Cln6 | ceroid-lipofuscinosis, neuronal 6
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Nervous system Vision/eye Cardiovascular system
12 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased prepulse inhibition | 2 supporting datasets | Cln6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.36x10-7 | ||
abnormal retina morphology | 1 supporting dataset | Cln6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.86x10-13 | ||
increased heart weight | 1 supporting dataset | Cln6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.57x10-5 | ||
decreased total body fat amount | 1 supporting dataset | Cln6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.97x10-5 |
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External links
No external links available for Cln6.
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Cln6tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Cln6tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Cln6tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Cln6tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Cln6tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |