Tiparp | TCDD-inducible poly(ADP-ribose) polymerase

GeneMGI:2159210Synonyms: PARP-7, DDF1, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hematopoietic system Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



scaly skin	1 supporting dataset	Tiparp^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Tiparp^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Tiparp^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Tiparp^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Tiparp^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tiparp.

Associated images

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Histopathology

There is no histopathology data found for Tiparp.

IMPC related publications

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External links

No external links available for Tiparp.

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*Tiparp^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tiparp^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tiparp^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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