Snx14 | sorting nexin 14

GeneMGI:2155664Synonyms: C330035N22Rik, YR-14

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Nervous system Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased exploration in new environment1 supporting datasetSnx14em1(IMPC)HheterozygoteEarly adult4.07x10-5 
decreased prepulse inhibition2 supporting datasetsSnx14em1(IMPC)HheterozygoteEarly adult8.3x10-11 
increased mean platelet volume1 supporting datasetSnx14em1(IMPC)HheterozygoteEarly adult1.21x10-5 
increased grip strength1 supporting datasetSnx14em1(IMPC)HheterozygoteEarly adult6.08x10-7 
preweaning lethality, complete penetrance1 supporting datasetSnx14em1(IMPC)HhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Snx14em1(IMPC)HExon Deletionmouse
Snx14tm1aNarlKO first allele (reporter-tagged insertion with conditional potential)es cell
Snx14tm380484(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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