Ube4a | ubiquitination factor E4A
Physiological systems
17 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Skeleton Cardiovascular system
10 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased lean body mass | 2 supporting datasets | Ube4aem1(IMPC)Tcp | homozygote | Early adult | 4.37x10-8 | ||
| impaired glucose tolerance | 1 supporting dataset | Ube4aem1(IMPC)Tcp | homozygote | Early adult | 3.67x10-10 | ||
| decreased bone mineral content | 2 supporting datasets | Ube4aem1(IMPC)Tcp | homozygote | Early adult | 1.82x10-6 | ||
| increased total body fat amount | 2 supporting datasets | Ube4aem1(IMPC)Tcp | homozygote | Early adult | 6.11x10-8 | ||
| shortened QT interval | 1 supporting dataset | Ube4aem1(IMPC)Tcp | homozygote | Early adult | 2.97x10-5 | ||
| enlarged lymph nodes | 1 supporting dataset | Ube4aem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| short tibia | 1 supporting dataset | Ube4aem1(IMPC)Tcp | homozygote | Early adult | 1.08x10-8 | ||
| abnormal bone structure | 1 supporting dataset | Ube4aem1(IMPC)Tcp | homozygote | Early adult | 4.88x10-5 |
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External links
No external links available for Ube4a.
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| Ube4aem1(IMPC)Tcp | Exon Deletion | | mouse |
| Ube4atm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ube4atm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |