Bicra | BRD4 interacting chromatin remodeling complex associated protein

GeneMGI:2154263Synonyms: Gltscr1

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Cardiovascular system Mortality/aging

14 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular hemoglobin1 supporting datasetBicraem1(IMPC)JheterozygoteEarly adult1.42x10-7 
abnormal tail morphology1 supporting datasetBicraem1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetBicraem1(IMPC)JhomozygoteEarly adultN/A * 
abnormal body wall morphology1 supporting datasetBicraem1(IMPC)JhomozygoteE18.5N/A * 
hemorrhage1 supporting datasetBicraem1(IMPC)JhomozygoteE18.5N/A * 
microphthalmia1 supporting datasetBicraem1(IMPC)JhomozygoteE18.5N/A * 
increased mean corpuscular volume1 supporting datasetBicraem1(IMPC)JheterozygoteEarly adult6.74x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bicraem1(IMPC)JExon Deletionmouse

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